Renal Thrombotic Microangiopathy in a Patient with Rheumatoid Arthritis and Antiphospholipid Syndrome: Successful Treatment with Cyclophosphamide Pulse Therapy and Anticoagulant.
スポンサーリンク
概要
- 論文の詳細を見る
A female patient with a history of migraines and chorea developed polyarthralgia at age 24 and was diagnosed with rheumatoid arthritis. In 1991 she was hospitalized because of impaired renal function and hypertension. Examination revealed thrombocytopenia and the presence of lupus anticoagulant. Antinuclear antibody was weakly positive, but anti-DNA antibody was negative, and no decrease in leukocyte count or complement level was observed. Rheumatoid arthritis with antiphospholipid syndrome was diagnosed. Renal biopsy showed renal thrombotic microangiopathy. This renal lesion was considered to be associated with antiphospholipid syndrome. Cyclophosphamide pulse therapy and anticoagulation therapy decreased proteinuria and improved renal function.(Internal Medicine 33: 484-487, 1994)
- 社団法人 日本内科学会の論文
著者
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Kondo Hirobumi
The Department Of Internal Medicine Kitasato University School Of Medicine
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Kobayashi Yutaka
The Department Of Medicine Kitasato University School Of Medicine
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TATENO Sumio
The Division of Nephrology, Department of Internal Medicine, Kitasato University School of Medicine
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NOMURA Masayo
The Division of Rheumatology, Department of Internal Medicine, Kitasato University School of Medicine
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OKADA Jun
The Division of Rheumatology, Department of Internal Medicine, Kitasato University School of Medicine
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KONDO Hirobumi
The Division of Rheumatology, Department of Internal Medicine, Kitasato University School of Medicine
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KOBAYASHI Yutaka
The Division of Nephrology, Department of Internal Medicine, Kitasato University School of Medicine
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OKADA Jun
The Department of Internal Medicine, Kitasato University, School of Medicine
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