Left Ventricular Hypertrophy was Infrequent in Patients Starting Dialysis after Undergoing a Strict Blood Pressure Control in the Pre-dialytic Period

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概要

• 論文の詳細を見る

• Objective We retrospectively investigated the factors influencing the left ventricular hypertrophy (LVH) occurrence in patients with chronic renal failure (CRF). Methods and Patients Blood pressure and echocardiographyically determined LVH were assessed in 110 patients on the basis of availability of monthly follow-up data obtained during the period of 2 years before the start of dialysis. When the patients showed the left ventricular mass index of not less than 125 g/m2, they were diagnosed as having LVH. Mean casual blood pressure distribution was classified into 5 groups: Group 1; <93 mmHg, Group 2; 93-100 mmHg, Group 3; 100-106 mmHg, Group 4; 106-114 mmHg and Group 5; >114 mmHg. Results LVH frequencies were 31.8, 72.7, 72.7, 81.8 and 95.5 (%) in Groups 1-5, respectively. Logistic regression showed that the factors influencing the progression of LVH were the duration of hypertension (per 1 year relative risk) (RR) 1.13, 95% confidential interval (CI) (1.01-1.26), treatment with angiotensin-converting enzyme inhibitors (ACE-I) (RR: 0.20, 95%CI: 0.04-0.99), pulse pressure (RR: 1.06, 95%CI: 1.00-1.11) and mean blood pressure (MBP). The RR of developing LVH increased progressively as MBP increased: Compared with LVH frequency in Group 1, RR of Group 2 was 4.38 (95%CI: 1.05-18.19), that of Group 3 was 5.50 (95%CI: 1.08-28.02), that of Group 4 was 5.66 (95%CI: 1.22-26.15), and that of Group 5 was 19.13 (95%CI: 1.75-209.4). Conclusion Strict blood pressure control and ACE-I treatment could prevent LVH in patients with CRF.(Internal Medicine 41: 925-930, 2002)

• 社団法人 日本内科学会の論文
• 2002-11-01

著者

• Shigematsu Takashi

  The Department Of Nephrology & Hypertension Aoto General Hospital Jikei University School Of Med

• Nakazato Takashi

  The Department Of Internal Medicine Sakura National Hospital

• Yamada Kenichi

  The Department Of Internal Medicine Sakura National Hospital

• KAWADA Takayuki

  the Department of Internal Medicine, Kimitsu Chu-o Hospital

• Kawada Takayuki

  The Department Of Internal Medicine Kimitsu Chu-o Hospital

関連論文

• "Hexatuple" Coronary Bypass With in Situ Arterial Grafts
• Left Ventricular Hypertrophy was Infrequent in Patients Starting Dialysis after Undergoing a Strict Blood Pressure Control in the Pre-dialytic Period

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