Renal Cell Carcinoma with Skull Base Metastasis Preceded by Paraneoplastic Signs in a Chronic Hemodialysis Patient.

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概要

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• A 59-year-old man who had received chronic hemodialysis developed left occipital pain and hypoglossal nerve palsy. He was diagnosed as having skull base metastasis from renal cell carcinoma related to acquired cystic kidney. Retrospective analysis revealed the patient had had elevated serum C-reactive protein and alkaline phosphatase levels before the symptoms appeared. Radiotherapy to the skull base relieved the pain. Finally he died with generalized metastases. Serum interleukin-6 levels measured during admission had been elevated, and interleukin-6 mRNA was detected in the autopsy specimen of renal cell carcinoma. Interleukin-6 might be involved in the etiology of paraneoplastic signs.(Internal Medicine 40: 924-930, 2001)

• 社団法人　日本内科学会の論文

著者

• Kuroda Yutaka

  The Division Of Nephrology

• Endo Kazunori

  The Department Of General Medicine

• Tabei Kaoru

  The Division Of Nephrology

• Okano Ryo

  The Department Of General Internal Medicine Omiya Medical Center Jichi Medical School

• Yamada Shigeki

  The Department Of Integrated Medicine Omiya Medical Center Jichi Medical School

• TABEI Kaoru

  the Division of Nephrology, Omiya Medical Center, Jichi Medical School

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• Renal Cell Carcinoma with Skull Base Metastasis Preceded by Paraneoplastic Signs in a Chronic Hemodialysis Patient
• Renal Cell Carcinoma with Skull Base Metastasis Preceded by Paraneoplastic Signs in a Chronic Hemodialysis Patient.

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