Preclinical Cushing's Syndrome Due to ACTH-independent Bilateral Macronodular Adrenocortical Hyperplasia with Excessive Secretion of 18-hydroxydeoxycorticosterone and Corticosterone
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概要
- 論文の詳細を見る
A 64-year-old woman developed hypertension and hypokalemia, due to ACTH-independent bilateral macronodular adrenocortical hyperplasia (AIMAH) with excessive secretion of 18-hydroxydeoxycorticosterone and corticosterone. Plasma cortisol did not show a diurnal rhythm, and was not suppressed by dexamethasone (8 mg). Plasma cortisol responded to ACTH and was increased by hypoglycemia without modifying ACTH levels. Radiological studies demonstrated that adrenal glands were enlarged with macronodules. Although the patient exhibited a low plasma renin activity and aldosterone levels, hypokalemia and hypertension were observed. Hormonal findings would support the hypothesis that the tumor of AIMAH originated from cells of the upper zona fasciculata.(Internal Medicine 41: 304-308, 2002)
- 社団法人 日本内科学会の論文
著者
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Katayama Shigehiro
埼玉医科大学 第四内科学教室
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Katayama Shigehiro
The Fourth Department Of Internal Medicine Satama Medical School
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Kitahama Shinji
The Fourth Department Of Internal Medicine Satama Medical School
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WADA Seiki
the Fourth Department of Internal Medicine, Satama Medical School
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TOGASHI Atsuhito
the Fourth Department of Internal Medicine, Satama Medical School
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INOUE Kiyoaki
the Fourth Department of Internal Medicine, Satama Medical School
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IITAKA Makoto
the Fourth Department of Internal Medicine, Satama Medical School
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Wada Seiki
The Fourth Department Of Internal Medicine Satama Medical School
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Iitaka Makoto
The Fourth Department Of Internal Medicine Satama Medical School
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Inoue Kiyoaki
The Fourth Department Of Internal Medicine Satama Medical School
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Togashi Atsuhito
The Fourth Department Of Internal Medicine Satama Medical School
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Katayama Shigehiro
埼玉医科大学 医学部内分泌内科･糖尿病内科
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