Acute Interstitial Nephritis with Polyclonal B Cell Infiltration and Development of Mantle Cell Lymphoma

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概要

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• A 69-year-old man with proteinuria, hematuria and abnormal renal and hepatic function developed acute renal failure. His clinical and laboratory examinations showed splenomegaly, edema, anemia and polyclonal hypergammaglobulinemia with high IgG levels. Renal biopsy showed interstitial nephritis with predominant B cell and plasma cell infiltration without monoclonality. After corticosteroid treatment, the patient showed remission in clinical symptoms and laboratory findings. However, one year later, he developed mantle cell lymphoma (MCL) with typical lymphocyte markers of cyclin Dl and CDS. When evaluated retrospectively, this patient appeared to have multicentric Castlemans disease initially and developed MCL later.(Internal Medicine 41: 1158-1162, 2002)

• 社団法人 日本内科学会の論文
• 2002-12-01

著者

• Wu Qiong

  Seventh Department Of Internal Medicine School Of Medicine Tokai University

• Endoh Masayuki

  Seventh Department Of Internal Medicine School Of Medicine Tokai University

• JINDE Kiichiro

  Seventh Department of Internal Medicine, School of Medicine, Tokai University

• YANAGI Hidetaka

  Seventh Department of Internal Medicine, School of Medicine, Tokai University

• Yanagi Hidetaka

  Seventh Department Of Internal Medicine School Of Medicine Tokai University

• Jinde Kiichiro

  Seventh Department Of Internal Medicine School Of Medicine Tokai University

• SAKAI Hideto

  The Seventh Department of Internal Medicine, School of Medicine, Tokai University

関連論文

• Acute Interstitial Nephritis with Polyclonal B Cell Infiltration and Development of Mantle Cell Lymphoma
• Acute Interstitial Nephritis with Polyclonal B Cell Infiltration and Development of Mantle Cell Lymphoma

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