Single Low-Dose Treatment with Praziquantel for Diphyllobothrium nihonkaiense Infections.

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概要

• 論文の詳細を見る

• Objective To investigate whether praziquantel is effective against diphyllobothriasis nihonkaiense at doses less than the conventional dose. Patients and Methods Fourteen Japanese men with diphyllobopthriasis nihonkaiense were treated with a single administration of praziquantel at 5-10 mg/kg. Results Twelve patients expelled a complete integrated Diphyllobothrium nihonkaiense with its scolex. One patient expelled an integrated D. nihonkaiense without its scolex, and one patient expelled 2 complete integrated D. nihonkaiense with their scolex, and an integrated D. nihonkaiense without its scolex. The lack of eggs in stool samples was confirmed in these 2 patients after the end of therapy. All patients had not expelled proglottides after the end of therapy for more than 1 year. No side effects were identified in any of the patients. Conclusion All patients were considered to be cured. Our results indicate that the oral administration of a single dose of praziquantel at 5-10 mg/kg is effective and safe against D. nihonkaiense infections.(Internal Medicine 42: 41-43, 2003)

• 社団法人　日本内科学会の論文

著者

• Ohnishi Kenji

  The Department Of Infections Diseases Tokyo Metropolitan Bokutoh General Hospital

• Kato Yasuyuki

  The Department Of Cardiovascular Surgery Osaka National Hospital

• KATO Yasuyuki

  The Department of Infectious Diseases, Tokyo Metropolitan Bokutoh General Hospital

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