Acute Antihypertensive Effects of Calcium Channel Blockers Are not Affected by Calcium Supplementation in Patients with Essential Hypertension.
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概要
- 論文の詳細を見る
The study was designed to investigate whether the acute antihypertensive effects of calcium channel blockers are affected by calcium supplementation in patients with essential hypertension. The antihypertensive effects of calcium channel blockers (oral manidipine or intravenous nicardipine) were studied before and during calcium supplementation (1200mg/day for 8 weeks) in 30 hospitalized patients with essential hypertension. The averages of systolic and diastolic blood pressure during a 24-hour period were not decreased by calcium supplementation. The acute antihypertensive effects of the calcium channel blockers nicardipine (0.25, 0.5, 1.5, 2.0μg/kg/min, intravenous infusion) or manidipine (20mg, once a day, orally) were not enhanced by calcium supplementation. Thus, calcium channel blockers can be safely combined with calcium supplementation in terms of blood pressure.
- International Heart Journal刊行会の論文
著者
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Dohi Yasuaki
Division Of Hypertension And Vascular Research Second Department Of Internal Medicine Nagoya City Un
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Miyagawa Koichi
Division Of Hypertension And Vascular Research Second Department Of Internal Medicine Nagoya City Un
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Kojima Masayoshi
Division Of Hypertension And Vascular Research Second Department Of Internal Medicine Nagoya City Un
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SATO Koichi
Division of Cardiovascular Medicine, Nagoya City East Medical Center
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DOHI Yasuaki
Division of Hypertension and Vascular Research, Second Department of Internal Medicine, Nagoya City University Hospital
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Sato Koichi
Division of Cardiology, Nagoya City East Medical Center
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MIYAGAWA Koichi
Division of Hypertension and Vascular Research, Second Department of Internal Medicine, Nagoya City University Hospital
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- Acute Antihypertensive Effects of Calcium Channel Blockers Are not Affected by Calcium Supplementation in Patients with Essential Hypertension.