Microvascular Geometry of the Rat Heart. Arteriolar and Venular Capillary Regions.

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概要

• 論文の詳細を見る

• The importance of realistic data regarding microvascular geometry for the understanding of oxygen transport to tissue cannot be underestimated. The purpose of the present investigation was therefore to determine the pattern of capillarization in rat myocardium. The histochemical method used in this study was novel in that it allowed for the discrimination of arteriolar capillary (AC) and venular capillary (VC) regions on the basis of color. Our preeminent finding was that systematic differences exist in microvascular geometry from arteriolar to venular capillary regions in normal rat myocardium. Specifically, VC regions are characterized by greater capillary density; more uniform capillary spacing; shorter segment lengths; and increased capillary diameter. These differences translate to significantly greater capillary length, surface and volume densities on the venular side of the capillary bed. In the face of lower PO2 values towards venules, this distinctive geometry would serve to provide advantageous geometric conditions for oxygen diffusion.

• International Heart Journal刊行会の論文

著者

• GAO Ming

  Physiology Section, Research Institute of Applied Electricity, Hokkaido University

関連論文

• Microvascular Geometry of the Rat Heart. Arteriolar and Venular Capillary Regions.

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