Clinical significance of ambulatory blood pressure monitoring. Evaluation of severity of hypertension, efficacy of treatment and effects on nighttime blood pressure.:Evaluation of Severity of Hypertension, Efficacy of Treatment and Effects on Nighttime Bl
スポンサーリンク
概要
- 論文の詳細を見る
Blood pressure (BP) obtained by the physician in his office and ambulatory BP recorded every hour throughout 24 hours with a noninvasive automated BP monitoring device were compared in 10 normotensives and 162 hypertensives. Casual BPs significantly correlated with averages in ambulatory BPs (ABPs) throughout the whole day, day (7 am-10 pm) and night (0-5 am). However, it was noted that 6 of 10 normotensives and all of the moderate to severe hypertensives had ABPs of more than 150/90mmHg at least once during the 24-hour period. The incidence of ABPs greater than 150/90mmHg among all readings was higher in untreated and treated hypertensives with diastolic BPs in the office of more than 105mmHg, and, when checked along with the clock time, higher not only in the morning but also in the evening. On the other hand, one-third or one-fifth of treated hypertensives with diastolic office BPs less than 90mmHg or between 90 and 105mmHg respectively had ABPs less than 150/90mmHg throughout the whole day. When the effect of nicardipine (60mg, t.i.d.) or slow-release nifedipine (27.3±3.0mg, b.i.d.) on minimum BP during the night was analyzed, long-acting nifedipine decreased BP throughout the night to levels not significantly different from normotensive controls, whereas short-acting nicardipine did not affect nighttime BPs. These results suggest that simple ABP monitoring throughout the day gives us useful information to evaluate the severity of hypertension and the efficacy of anti hypertensive medication as well as to avoid overtreatment with long-acting hypotensive agents resulting in a great fall in BP during sleep.
- International Heart Journal刊行会の論文
著者
-
Katayama Shigehiro
Fourth Department Of Internal Medicine Saitama Medical School
-
INABA Munemichi
Fourth Department of Medicine, Saitama Medical School
-
ISHII Jun
Fourth Department of Medicine, Saitama Medical School
-
MARUNO Yoshiko
Fourth Department of Medicine, Saitama Medical School
-
ITABASHI Akira
Fourth Department of Medicine, Saitama Medical School
-
OMOTO Akira
Fourth Department of Medicine, Saitama Medical School
関連論文
- Induction of Autoimmune Hypothyroidism and Subsequent Hyperthyroidism by TSH Receptor Antibodies following Subacute Thyroiditis: A Case Report
- Blood Pressure Control in Japanese Hypertensives with or without Type 2 Diabetes Mellitus
- CLOCK/BMAL1 is Involved in Lipid Metabolism via Transactivation of the Peroxisome Proliferator-activated Receptor (PPAR) Response Element
- A Patient with Severe Hypertriglyceridemia Associated with Anemia and Hypoalbuminemia
- Apoptosis of Endothelial Cells may be Mediated by Genes of Peroxisome Proliferator-activated Receptor γ1 (PPAR γ1) and PPARα Genes
- Effect of p53 Deficiency on External Vascular Cuff-Induced Neointima Formation
- Effects of disruption of p53 gene on vascular neointima formation
- Effect of Cilnidipine on Insulin Sensitivity in Patients with Essential Hypertension
- Antioxidant Treatment with α-Tocopherol Improves Erectile Function in Hypertensive Rats
- Is Renoprotection by Angiotensin Receptor Blocker Dependent on Blood Pressure? : The Saitama Medical School, Albuminuria Reduction in Diabetics with Valsartan (STAR) Study
- Treatment with Hypotensive Agents Affects the Impaired Relaxation of the Penile Corpus Cavernosum in Hypertensive Rats
- Erectile Dysfunction in Hypertensive Rats Results from Impairment of the Relaxation Evoked by Neurogenic Carbon Monoxide and Nitric Oxide
- Effects of a Low Dose of Indapamide, a Diuretic, Given Daily or Every-Other-Day on Blood Pressure and Metabolic Parameters
- Combined Treatment with an AT_1 Receptor Blocker and Angiotensin Converting Enzyme Inhibitor Has an Additive Effect on Inhibiting Neointima Formation via Improvement of Nitric Oxide Production and Suppression of Oxidative Stress
- Hyperinsulinemia in Relation to Hypertension and Other Coronary Risk Factors in Japanese Men.
- Effects of slow-release nifedipine on nighttime blood pressure.
- Clinical significance of ambulatory blood pressure monitoring. Evaluation of severity of hypertension, efficacy of treatment and effects on nighttime blood pressure.:Evaluation of Severity of Hypertension, Efficacy of Treatment and Effects on Nighttime Bl
- Effects of Captopril or Nitrendipine on Left Ventricular Collagen or Laminin B2 Gene Expression.