Evolution of cardiac involvement in progressive ophthalmoplegia with deleted mitochondrial DNA.

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概要

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• A 43-year-old woman with progressive external ophthalmoplegia developed a bifascicular block and dilatation of the right ventricle during 4 years of follow-up. Histochemical and electron microscopy studies detected mitochondrial abnormalities in ocular, skeletal muscle and cardiac biopsies. This case registers disease progression from the external ocular to the skeletal and cardiac muscles. Mitochondrial DNA was deleted in relation to the morphological abnormality.

• International Heart Journal刊行会の論文

著者

• Valente Maria

  Department Of Pathology University Hospital Of Padova

• ANGELINI Corrado

  Departments of Neurology University of Padua Medical School

• BUJA Gianfranco

  Department of Cardiology, University of Padua, Medical School

• VALENTE Maria

  Departments of Pathology University of Padua Medical School

• MELACINI Paola

  Departments of Cardiology University of Padua Medical School

• MICAGLIO Gianfranco

  Departments of Neurology University of Padua Medical School

• BUJA Gianfranco

  Departments of Cardiology University of Padua Medical School

関連論文

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• Arrhythmia Development in a Young Subject with Right Ventricular Cardiomyopathy. (Right Ventricular Dysplasia).
• Evolution of cardiac involvement in progressive ophthalmoplegia with deleted mitochondrial DNA.

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