Changes of Serum Pi Levels in Wistar-Kyoto rats (WKY), Spontaneously hypertensive rats (SHR) and Stroke-prone SHR (SHRSP)
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Serum Pi levels in SHRSP were markedly lower in comparison with those in WKY and SHR, while there were no differences in serum Ca levels among these 3 strains at any age of months after birth. Urinary Pi excretion in SHRSP under the condition of established severe hypertension without organic vascular changes (4-6 months after birth) was significantly more and PTH-C levels in SHRSP were significantly higher in comparison with those in SHR. Such higher levels of serum PTH-C seem to be related with lower serum levels and much urinary excretion of Pi, directly and/or indirectly, under the condition of established severe hypertension, in addition to maintenance of serum Ca levels.
- International Heart Journal刊行会の論文
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- Changes of Serum Pi Levels in Wistar-Kyoto rats (WKY), Spontaneously hypertensive rats (SHR) and Stroke-prone SHR (SHRSP)