Functional cardiac depression caused by defibrillator shocks. Quantitation of the safety factor for electrical defibrillation.:Quantitation of the Safety Factor for Electrical Defibrillation

スポンサーリンク

概要

• 論文の詳細を見る

• The overdose shock strengths required to depress ventricular contraction were determined for damped sinusoidal current in 7 metabolically supported, isolated contracting canine hearts. Each heart was suspended in an isoresistive and isotonic solution-through which the defibrillating shocks were delivered. Defibrillation thresholds were determined with standard damped sine wave shocks of 4.4-5.5msec duration. Then overdose shocks were delivered and the depressant effect on systolic left ventricular pressure was measured for shocks of 3-12 times threshold current. The minimum (threshold) current and energy densities required to defibrillate were 59.5±4.6mA/cm2 (average) and 3.12±0.2mJ/cm3. Increasing the shock strength above threshold produced a concomitant reduction of postshock left ventricular systolic pressure. The current and energy densities required to produce 50% depression (TD50) of left ventricular systolic pressure were 5.0 and 24.1 times the threshold current and energy densities respectively, indicating a wide safety margin using this criterion.

• International Heart Journal刊行会の論文

著者

• NIEBAUER M.J.

  Biomedical Engineering Center, Purdue University

• CARTER J.E.

  Biomedical Engineering Center, Purdue University

• BABBS C.F.

  Biomedical Engineering Center, Purdue University

• GEDDES L.A.

  Biomedical Engineering Center, Purdue University

• BOURLAND J.D.

  Biomedical Engineering Center, Purdue University

関連論文

• Functional cardiac depression caused by defibrillator shocks. Quantitation of the safety factor for electrical defibrillation.:Quantitation of the Safety Factor for Electrical Defibrillation

スポンサーリンク