Retinal arteriolar reactivity to vasodilators in stroke-prone hypertensive rats
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概要
- 論文の詳細を見る
Hydralazine and α-methyldopa administered per os, did not significantly lowered the blood pressure of SHRSP rats, in the 8, 16 and 24 week-old SHRSP in the doses used in this study.In group of 40 week-old SHRSP, both of the drugs did not lowered the blood pressure. However, the narrowing of the retinal arterioles was less progressive in the treated groups of SHRSP than in the untreated SHRSP.These findings may suggest that sclerotic alterations of the retinal arteriolar wall caused by long duration of hypertension are prevented by vasodilative agents such as hydralazine and α-methyldopa.
- International Heart Journal刊行会の論文
著者
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Yamagami Kiyoshi
Department of Cardiology, Osaka Rosai Hospital
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NARITA Kiyoharu
Department of Dental Material Science, School of Dentistry, Aichi-Gakuin University
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Yoshimoto Hiroshi
Department Of Internal Medicine Social Insurance Central General Hospital
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Maeda Syuji
Department of Ophthalmology, Hirosaki University School of Medicine
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Narita Kiyoharu
Department of Ophthalmology, Hirosaki University School of Medicine
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