Ca, P代謝に関する実験的研究Ca, P過剰食餌のラット胎仔におよぼす影響について

概要

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It is well established fact that calcium and phosphorus are vital requirement for the body. This study was carried out in order to examine whether or not teratogenic effects would appear in Wistar albino rats where the mother had been given a calcium and phosphorus deficient diet during pregnancy. 50 adult females were fed on a diet consisting of Sucrose 69%, Casein 20%, Soybean oil 5%, Salt mixture 5%, Vitamin mixture 0.5% and Choline chloride 0.5%. All rats were provided with distilled water for drinking. Results are as follows: 1) As for ossification retardation of the occipital bone in the groups fed on the said diet for the first 7 days and the middle 7 days, no difference was observed compared with the control group. 2) Beyond the above report, the experimental group was not found to be superior to the control group.
社団法人日本薬理学会の論文