Studies on sites of narcotics, hypnotics and analgesics on somatic afferent pathway (I)
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概要
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In order to clarify the sites of action of various narcotics, hypnotics and analgesics on the somatic afferent pathway, the effects of these drugs on electrical response (the primary, secondary and third response described by <I>Dempsey</I> etc.) in the central nervous system produced by the stimulation of the somatic nerve were studied by making experiments on rabbits and cats. From the results it was concluded that ether, chloral hydrate, urethane and myanesin paralysed the central nervous system extensively; barbiturates as amytal, dial, luminal, evipan and pentothal sodium affected the reticular structure of the mid brain, while morphine, bromide and aminopyrine the medial thalamic nuclei.
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