飼料中コレステロ-ルが成長中のニワトリの3-Hydroxy-3-Methylglutaryl CoA Reductase活性へ及ぼす影響〔英文〕
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概要
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This experiment was designed to evaluate the effect of dietary cholesterol on 3-hydroxy-3-methylglutaryl CoA (HMG-CoA) reductase activities in the liver and small intestine of chicks. Chicks were fed experimental diets for two weeks and then killed for the determination of the HMG-CoA reducates activities in the intestinal epithelial cell and hepatic microsomes. Activities of the HMG-CoA reductase in the liver and jejunum of chicks fed the cholesterol-supplemented diet were significantly lower than that of those fed the cholesterol-free diet. The enzyme activity in the jejunum was higher than in the ileum. When chicks were fed the cholesterol-supplemented diet, concentrations of esterified and free cholesterols in the serum and free cholesterol contents in the liver and epithelial cells of jejunum and ileum were significantly increased.
- 社団法人 日本畜産学会の論文