pulse radiolysisの生体高分子への応用
スポンサーリンク
概要
- 論文の詳細を見る
The present article outlines the recent development of pulse radiolysis studies on aqueous solutions of enzyme proteins.<BR>Pulse radiolysis method has provided much information on fast process induced by a short-lived perturbation of various substances. In recent few years, the results from an application of the method to aqueous solutions of biological macromolecules have been increasingly accumulated. Particularly an extensive work on enzyme proteins reveals that protein molecule reacts with the primary radicals produced in radiolysis of water to give a characteristic transient absorption and above 10<SUP>10</SUP>M<SUP>-1</SUP>sec<SUP>-1</SUP> is determined as a rate constant for the reaction. Studies on selective reactions of inorganic radical anions with proteins suggest that radiation chemical technique could provide a new method for investigation of molecular nature of biological substances. Finally the reactivity of protein towards OH radicals is discussed in terms of tertiary structure of the protein molecule.
- 日本生物物理学会の論文
著者
関連論文
- Reactions of Hydroxyl Radicals with Nucleic Acid Bases and the Related Compounds in Gamma-irradiated Aqueous Solution
- Photoreduction of Ferricvtcchrome C in the Presence and Absence of Electron-Donor
- Transient Absorptions over the Range 600-800 nm Observed in Flash-Photolysis of Aqueous Solutions of Indole
- Reactivity of Aliphatic Peptides toward Hydroxyl Radicals in Aqueous Solution
- Reactivities of Enzymes toward Hydroxyl Radicals
- Radiation-chemical Discussion on Inverse Dose-rate Effect Observed in Radiation-induced Strand Breaks of Plasmid DNA
- pulse radiolysisの生体高分子への応用