シゾフィランの三重らせん構造と抗腫瘍活性

概要

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A series of studies on the conformation, properties, and antitumor activity of schizophyllan, an extracellular β-1, 3-D-glucan, in aqueous solution are reviewed. The polysaccharide exists as a triple-stranded helix in aqueous solution if the molecular weight is higher than 10<SUP>5</SUP>. This helical structure is responsible for the potent antitumor activity of the glucan.
日本生物物理学会の論文