遺伝情報を読む:スプライス信号配列の数量化分析

概要

論文の詳細を見る
The signals which direct excision of infrons from mRNA precursors in higher eukaryotes genes are not well understood. Although a consensus sequence, CA AG/GT AG AGT, has been proposed with the 5-splice site actual 5-splice site sequences differ from it to a greater or lesser degree. In the present paper, nucleotide sequences were transformed into categorical data, and quantification analysis developed by Hayashi was applied to such a system. Two classes of 5-splice site sequences and sequences other than 5-splice site were discriminated most distinctly. This approach was useful to know those factors which characterize 5-splice signal sequences.
日本生物物理学会の論文