Isolation of Fusarium sp. from a Claw of a Dog with Onychomycosis

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概要

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• An 8-year-old male Golden retriever had lameness and claw abnormality in the second digit of the left forelimb. Radiograph revealed osteomyelitis in distal phalanx bone of the affected limb. Microscopic examination of the claw revealed numerous hyphae in the claw matrix. Fungal DNA fragments coding ribosomal internal transcribed spacer region (ITS) were detected from the claw matrix as well as fungal colonies of the clinical isolates by PCR. Nucleotide sequencing revealed that the amplicons shared >99% homology with Fusarium sp. Therapy including oral itraconazole resulted in regrowth of a new claw, in which no hyphae were detected. To the authors knowledge, this is the first case report of canine onychomycosis, in which Fusarium sp. was isolated from the affected claw.

著者

• SEKIGUCHI Maiko

  Department of Veterinary Internal Medicine, Faculty of Agriculture, Tokyo University of Agriculture

• KANO Rui

  Laboratory of Veterinary Pathobiology, Department of Veterinary Medicine, College of Bioresource Sci

• NISHIFUJI Koji

  Laboratory of Veterinary Internal Medicine, Faculty of Agriculture, Tokyo University of Agriculture and Technology

• NAMITOME Kazuko

  Laboratory of Veterinary Internal Medicine, Faculty of Agriculture, Tokyo University of Agriculture and Technology

• IWASAKI Toshiroh

  Laboratory of Veterinary Internal Medicine, Faculty of Agriculture, Tokyo University of Agriculture and Technology

• KANESHIMA Takashi

  Mizuhodai Animal Hospital

関連論文

• Isolation of Fusarium sp. from a Claw of a Dog with Onychomycosis
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