Efficacy of Aripiprazole in Sulpiride-induced Tardive Oromandibular Dystonia
スポンサーリンク
概要
- 論文の詳細を見る
Tardive dystonia is a side effect of dopamine receptor-blocking agents, which are mainly used as antipsychotic drugs. The treatment of tardive dystonia is difficult and often unsuccessful. An 82-year-old woman experienced mandibular deviation to the left due to spasm of the masticatory muscles with involuntary chewing movement and Parkinsonism. She had been treated with sulpiride for motility disorder for 5 years. Parkinsonism almost disappeared after the withdrawal of sulpiride, but tardive oromandibular dystonia showed no improvement. Aripiprazole treatment at 3 mg/day improved tardive oromandibular dystonia without worsening Parkinsonism. Low-dosage aripiprazole may be effective for tardive oromandibular dystonia in patients with no other psychiatric disorder.
著者
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Imai Noboru
Department of Chemistry, Faculty of Science, The University of Tokyo
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Imai Noboru
Department of Neurology, Shizuoka Red Cross Hospital, Japan
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Ikawa Masako
Department of Oral Surgery, Shizuoka-Shimizu Municipal Hospital, Japan
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