Tick-Encoded Serine Proteinase Inhibitors (Serpins); Potential Target Antigens for Tick Vaccine Development.

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概要

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• Immunological protection of hosts against tick infestation is at present the most practically sustainable alternative tick control method to the current use of acaricides that is riddled with serious limitations. The current focus of tick vaccine research is the identification, cloning and in vitro production of recombinant tick vaccine candidate antigens. We have examined a selected number of reports on the roles of parasite-encoded members of the serine proteinase inhibitor (serpin) superfamily in modulation of mammalian anti-parasite defense and developed some food for thought commentaries on the possibility of targeting this class of proteins for anti-tick vaccine development.

• 公益社団法人 日本獣医学会の論文

著者

• SUGIMOTO Chihiro

  Graduate School of Veterinary Medicine, Hokkaido University

関連論文

• Analysis of Immunodominant Piroplasm Surface Protein Genes of Benign Theileria Parasites Distributed in China and Korea by Allele-Specific Polymerase Chain Reaction
• Tick-Encoded Serine Proteinase Inhibitors (Serpins); Potential Target Antigens for Tick Vaccine Development.

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