Acquired Factor V Inhibitor in a Patient with a Mechanical Aortic Valve under Warfarin Therapy
スポンサーリンク
概要
- 論文の詳細を見る
An 84-year-old woman under warfarin therapy, who had undergone mechanical valve replacement 29 months previously, developed coagulation abnormalities after antibiotic treatment for pyelonephritis. Laboratory findings included PT at 47.6 sec, activated thromboplastin time (APTT) at 147 sec, factor V (FV) activity of 4% and FV inhibitor of 8 BU. Although overt bleeding was not observed, administration of prednisolone was started. Her coagulation abnormalities were rapidly normalized. It was later determined that the patient had received bovine thrombin at surgery. The presence of a FV inhibitor should be considered in the differential diagnosis in patients demonstrating an unexpected prolongation of PT under warfarin therapy following surgery.
著者
-
Mita Hiroaki
Department Of Molecular Biology Cancer Research Institute Sapporo Medical University
-
Okumura Toshikatsu
Department Of General Medicine Asahikawa Medical College
-
Nozu Tsukasa
Department Of Comprehensive Medicine Hokkaido University Hospital
関連論文
- Sonic hedgehog derived from human pancreatic cancer cells augments angiogenic function of endothelial progenitor cells
- Lipopolysaccharide induces adipose differentiation-related protein expression and lipid accumulation in the liver through inhibition of fatty acid oxidation in mice
- Epigenetic inactivation of RASSF2 in oral squamous cell carcinoma
- Neurobiological Basis of Controlling Posture and Locomotion
- Acquired Factor V Inhibitor in a Patient with a Mechanical Aortic Valve under Warfarin Therapy
- Inhibition of cell invasion and morphological change by troglitazone in human pancreatic cancer cells
- PPARγ ligand-induced apoptosis through a p53-dependent mechanism in human gastric cancer cells
- Prevalence of functional dyspepsia in an outpatient clinic with primary care physicians in Japan
- Intracisternal injection of orexin-A prevents ethanol-induced gastric mucosal damage in rats
- Frequent Early Discontinuation of SSRI Prescribed by Primary Care Physicians in Young Males in Japan
- Role of orexin in central regulation of gastrointestinal functions
- Severe Hyponatremia in Association with I131 Therapy in a Patient with Metastatic Thyroid Cancer
- Repetitive rectal painful distention induces rectal hypersensitivity in patients with irritable bowel syndrome
- Inadequate health care-seeking behavior of Japanese patients with functional gastrointestinal disorders: a preliminary survey
- Corticotropin-releasing factor induces rectal hypersensitivity after repetitive painful rectal distention in healthy humans
- Emphysematous cystitis with air bubbles in the inferior vena cava
- Clinical characteristics of asymptomatic esophagitis
- Brain or gut? Site of action of adrenomedullin to regulate gut motility
- Endogenous orexin-A in the brain mediates 2-deoxy-D-glucose-induced stimulation of gastric motility in freely moving conscious rats