Mefloquine Treatment in a Patient Suffering from Progressive Multifocal Leukoencephalopathy after Umbilical Cord Blood Transplant

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概要

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• We report herein the case of a 37-year-old man who developed probable progressive multifocal leukoencephalopathy (PML) following an umbilical cord blood transplant. The patient showed favorable clinical, neuroradiological and virological responses after treatment with mefloquine, an anti-malarial drug. Mefloquine may offer some benefits as a treatment for PML in patients with or without human immunodeficiency virus type-1 infection. This report highlights the need to gather sufficient data to confirm the efficacy of mefloquine against this devastating viral disease of the central nervous system.

• 社団法人 日本内科学会の論文

著者

• Tanaka Kozue

  Division of Neurology, Tokyo Metropolitan Cancer and Infectious Disease Center-Komagome Hospital

• Kishida Shuji

  Division of Neurology, Tokyo Metropolitan Cancer and Infectious Disease Center-Komagome Hospital

関連論文

• Mefloquine Treatment in a Patient Suffering from Progressive Multifocal Leukoencephalopathy after Umbilical Cord Blood Transplant

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