Severe Hypercalcemia Associated with Hepatocellular Carcinoma Secreting Intact Parathyroid Hormone: A Case Report
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概要
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Here we describe a 73-year-old woman with hypercalcemia caused by a hepatocellular carcinoma (HCC) secreting intact parathyroid hormone (iPTH). Serum tumor markers and dynamic CT findings indicated a diagnosis of HCC. The source of the elevated serum iPTH was not obvious. Transarterial chemoembolization (TACE) was effective against the HCC, and the serum iPTH level fell to within the normal range, suggesting a correlation between the carcinoma and the iPTH. About 2 months later, the tumor had grown and the serum calcium level increased leading to physical deterioration and death. This clinical course suggested that HCC can ectopically secrete iPTH.
著者
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Abe Yoko
Department Of Applied Biological Science Faculty Of Science And Technology Tokyo University Of Scien
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Tachibana Yasuhiro
Department Of Applied Chemistry Graduate School Of Engineering Osaka University
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Makiyama Hiroaki
Department Of Gastroenterology Hokkaido University Graduate School Of Medicine
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Abe Yoko
Department of Gastroenterology and Hepatology, Kitami Red Cross Hospital, Japan
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Fujita Yomo
Department of Gastroenterology and Hepatology, Kitami Red Cross Hospital, Japan
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Kamada Go
Department of Gastroenterology and Hepatology, Kitami Red Cross Hospital, Japan
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Uebayashi Minoru
Department of Gastroenterology and Hepatology, Kitami Red Cross Hospital, Japan
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Makiyama Hiroaki
Department of Gastroenterology and Hepatology, Kitami Red Cross Hospital, Japan
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