The Crystal Structure of SDR-Type Pyridoxal 4-Dehydrogenase of Mesorhizobium loti
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概要
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Pyridoxal 4-dehydrogenase catalyzes the irreversible oxidation of pyridoxal to 4-pyridoxolactone and is involved in degradation pathway I of pyridoxine, a vitamin B6 compound. Its crystal structure was elucidated for the first time. Molecular replacement with (S)-1-phenylthanol dehydrogenase (PDB code 2EW8) was adopted to determine the tertiary structure of the NAD+-bound enzyme.
著者
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Mikami Bunzo
Division Of Applied Life Science Graduate School Of Agriculture Kyoto University
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KOBAYASHI Jun
Faculty of Medicine, Department of Parasitology, University of Ryukyus
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CHU Huy
Faculty of Agriculture and Agricultural Science Program, Graduate School of Integral Arts and Scienc
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YAGI Toshiharu
Faculty of Agriculture and Agricultural Science Program, Graduate School of Integral Arts and Scienc
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