Identification of Novel Nuclear Protein Interactions with the N-Terminal Part of Filamin A

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概要

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• Since certain missense mutations in the N-terminal part of filamin A (FLNA) cause inherited skeletal malformation, we screened for proteins that bind to this part of FLNA. We identified two nuclear proteins that are specifically associated with the N-terminal region of FLNA. This suggests more extensive nuclear function of filamin than expected.

著者

• SUGIMOTO Kenji

  Graduate School of Information Science, Nara Institute of Science and Technology

• Qiu Hao

  Graduate School of Life and Environmental Sciences, Osaka Prefecture University

• Nomiyama Ryosuke

  Graduate School of Life and Environmental Sciences, Osaka Prefecture University

• Moriguchi Keisuke

  Graduate School of Life and Environmental Sciences, Osaka Prefecture University

• FUKADA Takashi

  Graduate School of Life and Environmental Sciences, Osaka Prefecture University

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• Identification of Novel Nuclear Protein Interactions with the N-Terminal Part of Filamin A

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