3-Hydroxymethylglutaryl Flavonol Glycosides from a Mongolian and Tibetan Medicine, Oxytropis racemosa
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概要
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Three new flavonol 3-O-glycosides, rhamnetin 3-O-[(S)-3-hydroxy-3-methyl-glutaroyl(1→6)]-β-D-glucopyranoside (1), rhamnocitrin 3-O-[(S)-3-hydroxy-3-methylglutaroyl(1→6)]-β-D-glucopyranoside (2), and isorhamnetin 3-O-[(S)-3-hydroxy-3-methylglutaroyl(1→6)]-α-L-rhamnopyranosyl(1→2)-β-D-glucopyranoside (3), along with 13 known compounds, were isolated from Oxytropis racemosa TURCZ. Their structures were deduced by means of spectroscopic methods and chemical evidence. 2 and 6 showed cytotoxic activities against HCT-8 (IC50 6.38 μM) and A549 (IC50 5.20 μM), respectively.
著者
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Song Shuang
Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine (Ministr
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Zheng Xiuping
Inner Mongolia Pharmaceutical Industrial Institute Co., Ltd.
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Liu Weidong
Inner Mongolia Pharmaceutical Industrial Institute Co., Ltd.
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Du Ruifang
Inner Mongolia Pharmaceutical Industrial Institute Co., Ltd.
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Bi Lifu
Inner Mongolia Medical College
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Zhang Peicheng
Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine (Ministr
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Zhang Peicheng
Key Lab. Of Bioactive Substances And Resources Utilization Of Chinese Herbal Medicine (ministry Of E
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Zhang Peicheng
Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine (Ministry of Education), Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College
関連論文
- 3-Hydroxymethylglutaryl Flavonol Glycosides from a Mongolian and Tibetan Medicine, Oxytropis racemosa
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