Anticonvulsant Activity and Toxicity Evaluation of CuII and ZnII Metal Complexes Derived from Triazole-Quinoline Ligands

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概要

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• A novel CuII and ZnII complexes of triazolo-quinoline derivatives were synthesized by in situ method and were characterized by the spectro-analytical methods and their pharmacological properties were evaluated. The compound C3 has exhibited promising anticonvulsant activity towards the electroshock induced seizures in Wistar rats and possesses low toxicity, providing a high safety profile.

• 社団法人 日本薬学会の論文

著者

• Kulkarni Naveen

  Department of Studies in Chemistry, Karnatak University

• Budagumpi Srinivasa

  Department of Studies in Chemistry, Karnatak University

• Kurdekar Gurunath

  Department of Studies in Chemistry, Karnatak University

• Revankar Vidyanand

  Department of Studies in Chemistry, Karnatak University

• Didagi Suresh

  Luqman College of Pharmacy

• Revankar Vidyanand

  Department Of Chemistry Karnatak University

関連論文

• Anticonvulsant Activity and Toxicity Evaluation of CuII and ZnII Metal Complexes Derived from Triazole-Quinoline Ligands
• Architecture of a Novel Binucleating SNONS Compartmental Ligand : Physico-Chemical Investigation of Its Metal Complexes

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