Butyrolactones from the Fungus Aspergillus terreus BCC 4651
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概要
- 論文の詳細を見る
Two new butenolides, butyrolactones VI (1) and VII (2), were isolated together with six known compounds, butyrolactones I (3), II (4), IV (5), and V (6), aspernolide B (7), and bisdethiodi(methylthio)acetylaranotin (8) from the fungus Aspergillus terreus BCC 4651. Compound 8, exhibiting a minimum inhibitory concentration (MIC) value of 1.56 μg/ml against Mycobacterium tuberculosis H37Ra, proved to be the antimycobacterial principle from the culture of this fungus. On the other hand, butyrolactone V (6) showed antiplasmodial activity against Plasmodium falciparum K1 with an IC50 of 7.9 μg/ml.
著者
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Haritakun Rachada
National Center For Genetic Engineering And Biotechnology National Science And Technology Developmen
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Boonyuen Nattawut
National Center for Genetic Engineering and Biotechnology (BIOTEC), Thailand
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Rachtawee Pranee
National Center For Genetic Engineering And Biotechnology Tha
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Chanthaket Rungtiwa
National Center for Genetic Engineering and Biotechnology, Thailand
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Isaka Masahiko
National Center for Genetic Engineering and Biotechnology, Thailand
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Isaka Masahiko
National Center For Genetic Engineering And Biotechnology (biotec)
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Boonyuen Nattawut
National Center for Genetic Engineering and Biotechnology, Thailand
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