Synthesis, Characterization and Biological Evaluation of Mononuclear Co(II), Ni(II), Cu(II) and Pd(II) Complexes with New N2O2 Schiff Base Ligands

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概要

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• New tetradentate N2O2 donor Schiff bases and their mononuclear Co(II), Ni(II), Cu(II), and Pd(II) complexes were synthesized and characterized extensively by IR, 1H-, 13C-NMR, mass, ESR, conductivity measurements, elemental and thermal analysis. Specifically the magnetic and electronic spectral measurements demonstrate the octahedral structures of cobalt(II), nickel(II) complexes and square planar geometries of copper(II), palladium(II) complexes. All the ligands and complexes were screened for their in vitro antibacterial activity against two Gram-positive bacteria (Bacillus subtilis, Staphylococcus aureus) and two Gram-negative bacteria (Escherichia coli, Klebsiella pneumonia). In this study, Pd(II) complexes exhibited potent antibacterial activity against B. subtilis, S. aureus whereas other metal complexes also exerted good activity towards all tested strains even than standard drugs streptomycin and ampicillin.

著者

• Budige Geeta

  Department of Chemistry, Kakatiya University

• Puchakayala Muralidhar

  Department of Chemistry, National Dong Hwa University

• Kongara Shobha

  Department of Chemistry, Kakatiya University

• Hu Anren

  Department of Laboratory Medicine and Biotechnology, Tzu Chi University

• Vadde Ravinder

  Department of Chemistry, Kakatiya University

関連論文

• Synthesis, Characterization and Biological Evaluation of Mononuclear Co(II), Ni(II), Cu(II) and Pd(II) Complexes with New N2O2 Schiff Base Ligands

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