A Case of Severe Thrombocytopenia in a Patient with Chronic Hepatitis C Caused by a Single Administration of Pegylated Interferon Alpha 2a Subsequent to 48 Weeks of Pegylated Interferon Alpha 2b Plus Ribavirin Therapy
スポンサーリンク
概要
- 論文の詳細を見る
A 54-year-old female with chronic hepatitis C developed severe thrombocytopenia after a single administration of Peg-IFN alpha 2a subsequent to 48 weeks of Peg-IFN alpha-2b plus ribavirin therapy. The platelet count decreased from 11.3×104 /mm3 to 1.6×104 /mm3. Blood test and bone marrow aspiration examination indicated that an immunological mechanism was considered for the etiology of platelet decrease. Fifty mg of prednisolone was administered and the platelet count gradually increased to the normal range. This case is very instructive since severe thrombocytopenia did not occur during 48 weeks of Peg-IFN alpha-2b plus ribavirin therapy, but occurred after a single subcutaneous administration of Peg-IFN alpha-2a during a subsequent course.
著者
-
KATO Hideaki
Department of Gastroenterology, Toyokawa City Hospital
-
Fujishiro Takuya
Department of Gastroenterology, Narita Memorial Hospital
-
Narita Makoto
Department of Gastroenterology, Narita Memorial Hospital
関連論文
- Rapid analysis of Clostridium difficile strains recovered from hospitalized patients by using the slpA sequence typing system
- A Case of Severe Thrombocytopenia in a Patient with Chronic Hepatitis C Caused by a Single Administration of Pegylated Interferon Alpha 2a Subsequent to 48 Weeks of Pegylated Interferon Alpha 2b Plus Ribavirin Therapy
- Acupuncture Stimulates the Release of Serotonin, but Not Dopamine, in the Rat Nucleus Accumbens
- A randomized controlled trial of consensus interferon with or without lactoferrin for chronic hepatitis C patients with genotype 1b and high viral load
- Hepatitis B virus genotype G is an extremely rare genotype in Japan
- Alterations of DNA methylation and histone modifications contribute to gene silencing in hepatocellular carcinomas
- Evaluation of anti-hepatitis E virus (HEV) immunoglobulin A in a serological screening for HEV infection
- Spontaneous regression of hepatocellular carcinoma : two case reports and a literature review
- Regression of esophageal papillomatous polyposis caused by high-risk type human papilloma virus
- Metastatic germ cell tumor of the lung masquerading as primary rhabdomyosarcoma
- Pyogenic granuloma of the stomach successfully treated by endoscopic resection after transarterial embolization of the feeding artery
- The excitation of a charged string passing through a shock wave in a charged Aichelburg-Sexl spacetime (時空特異点とその周辺)
- Divided-Dose Administration of Miglitol just before and 15 Minutes after the Start of a Meal Smoothes Postprandial Plasma Glucose Excursions and Serum Insulin Responses in Healthy Men
- Effects of the Initial Heat-Up Period on a Two-Droplet Array Burning at High Pressure in Microgravity
- Diffuse Intrasinusoidal Liver Metastasis of Small Cell Lung Cancer Causing Fulminant Hepatic Failure: CT Findings - A Case Report
- Two von Recklinghausen's disease cases with pheochromocytomas and gastrointestinal stromal tumors (GIST) in combination
- Forensic studies of brain vulnerability and resistance : Ischemia-induced dopamine and serotonin releases in the rat nucleus accumbens
- Enterovesical fistula complication in B-cell-type lymphoma of the small intestine