Miniaturized Time-of-Flight Mass Spectrometers for Bioagent Detection and Identification.

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概要

• 論文の詳細を見る

• This paper summarizes a number of instrumental designs and configurations that have been developed by the Middle Atlantic Mass Spectrometry Laboratory for the miniaturization of time-of-flight mass spectrometers that will be used in environmental, bioagent detection, and diagnostics applications. All are "linear" designs, that is: ions are focused to a detector located within a line-of-sight of the ion source; no reflectrons are used. All are also "dynamic" instruments, using pulsed ion extraction and/or other time-dependent electric fields. These mass analyzers have flight paths of approximately 3 inches, with mass resolutions of up to one part in 1200 and mass ranges over 66 kdaltons. The use of non-homogeneous electric fields is also proposed to further improve that performance. Some examples are given for the analysis of peptides and bacterial spores.

• 日本質量分析学会の論文

著者

• Hardy Andy

  Middle Atlantic Mass Spectrometry Laboratory Department Of Pharmacology And Molecular Sciences Johns

• Gardner Ben

  Middle Atlantic Mass Spectrometry Laboratory Department Of Pharmacology And Molecular Sciences Johns

• Cotter Robert

  Middle Atlantic Mass Spectrometry Laboratory Department Of Pharmacology And Molecular Sciences Johns

• English Robert

  Middle Atlantic Mass Spectrometry Laboratory Department Of Pharmacology And Molecular Sciences Johns

• Warscheid Bettina

  Department Of Chemistry And Biochemistry University Of Maryland

• GARDNER Ben

  Middle Atlantic Mass Spectrometry Laboratory, Department of Pharmacology and Molecular Sciences, Johns Hopkins University School of Medicine

関連論文

• Miniaturized Time-of-Flight Mass Spectrometers for Bioagent Detection and Identification (ノーベル化学賞記念特集号/TMS特集号(3))
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• Miniaturized Time-of-Flight Mass Spectrometers for Bioagent Detection and Identification.

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