Adaptation beyond the Stress Response: Cell Structure Dynamics and Population Heterogeneity in Staphylococcus aureus

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概要

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• Staphylococcus aureus, a major opportunistic pathogen responsible for a broad spectrum of infections, naturally inhabits the human nasal cavity in about 30% of the population. The unique adaptive potential displayed by S. aureus has made it one of the major causes of nosocomial infections today, emphasized by the rapid emergence of multiple antibiotic-resistant strains over the past few decades. The uncanny ability to adapt to harsh environments is essential for staphylococcal persistence in infections or as a commensal, and a growing body of evidence has revealed critical roles in this process for cellular structural dynamics, and population heterogeneity. These two exciting areas of research are now being explored to identify new molecular mechanisms governing these adaptational strategies.

• 日本微生物生態学会・日本土壌微生物学会の論文

著者

• Takeyasu Kunio

  Graduate School Of Biostudies Kyoto University

• Tanaka Yoshikazu

  Faculty of Advanced Life Science, Hokkaido Univ.

• OHNIWA Ryosuke

  Graduate School of Biostudies, Kyoto University

• Morikawa Kazuya

  Graduate School of Comprehensive Human Sciences, University of Tsukuba

• Ohta Toshiko

  Graduate School of Comprehensive Human Sciences, University of Tsukuba

• Msadek Tarek

  Biology of Gram-Positive Pathogens, Institut Pasteur

• Ohniwa Ryosuke

  Graduate School Of Biostudies Kyoto University

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