Chromeno[2,3-d]pyrimidine-triones Synthesis by a Three-Component Coupling Reaction

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概要

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• A simple and one-pot synthesis of new chromeno[2,3-d]pyrimidine-triones by a three-component condensation reaction of barbituric acids, aldehydes and cyclohexane-1,3-diones in refluxing ethanol in the presence of p-toluenesulfonic acid (p-TSA) for 3—10 h is reported. Two cyclohexane-1,3-diones, four barbituric acids and six substituted aldehydes were chosen for the library validation. Prominent among the advantages of this new method are operational simplicity, good yields and easy work-up procedures employed.

• 公益社団法人　日本薬学会の論文

著者

• BAZGIR Ayoob

  Department of Chemistry, Shahid Beheshti University

• Ghahremanzadeh Ramin

  Department Of Chemistry Shahid Beheshti University

• Fereshtehnejad Fatemeh

  Department of Chemistry, Shahid Beheshti University

• Bazgir Ayoob

  Department Of Chemistry Shahid Beheshti University

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• Chromeno[2,3-d]pyrimidine-triones Synthesis by a Three-Component Coupling Reaction
• One-Pot Synthesis and Antibacterial Activities of Novel 1H-Pyridazino [1,2-a] indazole-1,6,9 (2H,11H)-triones

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