Novel Melphalan and Chlorambucil Derivatives of 2,2,6,6-Tetramethyl-1-piperidinyloxy Radicals: Synthesis, Characterization, and Biological Evaluation in Vitro
スポンサーリンク
概要
- 論文の詳細を見る
A series of spin-labeled melphalan and chlorambucil derivatives, coupling the alkylating agents with 2,2,6,6-tetramethyl-1-piperidinyloxy (TEMPO) radicals, were synthesized, characterized, and their biological properties in vitro were evaluated. These compounds showed much higher cytotoxic activity against human leukemia cell line K562 in vitro than their parent compounds.
著者
-
Zhao Hongli
Key Laboratory for Advanced Materials, and Research Center of Analysis and Test, East China Universi
-
Meng Xianjiang
Key Laboratory for Advanced Materials, and Research Center of Analysis and Test, East China Universi
-
Yuan Huihui
Key Laboratory for Advanced Materials, and Research Center of Analysis and Test, East China Universi
-
Lan Minbo
Key Laboratory for Advanced Materials, and Research Center of Analysis and Test, East China Universi
-
Meng Xianjiang
Key Laboratory for Advanced Materials, and Research Center of Analysis and Test, East China University of Science and Technology
-
Lan Minbo
Key Laboratory for Advanced Materials, and Research Center of Analysis and Test, East China University of Science and Technology
-
Yuan Huihui
Key Laboratory for Advanced Materials, and Research Center of Analysis and Test, East China University of Science and Technology
-
Zhao Hongli
Key Laboratory for Advanced Materials, and Research Center of Analysis and Test, East China University of Science and Technology
関連論文
- Novel Melphalan and Chlorambucil Derivatives of 2,2,6,6-Tetramethyl-1-piperidinyloxy Radicals: Synthesis, Characterization, and Biological Evaluation in Vitro
- Disposable Screen-printed Bismuth Electrode Modified with Multi-walled Carbon Nanotubes for Electrochemical Stripping Measurements