Elucidation of the Metabolic Pathways of Selenium and Arsenic by Analytical Toxicology

スポンサーリンク

概要

• 論文の詳細を見る

• Hyphenated analytical techniques, such as high-performance liquid chromatography-inductively coupled plasma-mass spectrometry (HPLC-ICP-MS) and HPLC-electrospray ionization (ESI)-MS, are powerful tools for evaluating the elemental (HPLC-ICP-MS) and molecular (ESI-MS) speciation of metalloids, such as selenium (Se) and arsenic (As). Because the toxicity of metalloids is highly dependent upon the chemical forms that are present in vivo, toxicological assessment must include both the intact compound and its metabolites. We investigated the metabolic pathways of Se and As compounds and their metabolites using HPLC-ICP-MS and HPLC-ESI-MS.

著者

• Kobayashi Yayoi

  Environmental Health Sciences Division, National Institute for Environmental Studies

関連論文

• Elucidation of the Metabolic Pathways of Selenium and Arsenic by Analytical Toxicology
• The Role of Glutathione in the Metabolism and Detoxification of Trivalent Arsenicals (特集1:若手が拓く微量元素研究の最前線)

スポンサーリンク