IgG4-related Lung Disease in a Worker Occupationally Exposed to Asbestos
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概要
- 論文の詳細を見る
A case of IgG4-related lung disease in a worker who had been exposed to asbestos is described. The patient had nocturnal cough and wheeze that responded to inhaled corticosteroid, and the radioallergosorbent test was positive against common allergens, suggesting an association with atopic asthma. IgE elevation is reported in asbestos-exposed workers, and asbestos exposure may cause atopic conditions. Predominance of Th2 cytokines and up-regulation of regulatory T lymphocytes have been reported in IgG4-related disease. IgG4-related disease may occur from hypersensitivity of the regulatory immune system to atopic conditions. Asbestos exposure may be a causal factor of IgG4-related disease.
著者
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SUDA Takafumi
The Second Department of Internal Medicine, Hamamatsu University School of Medicine
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Toyoshima Mikio
Department of Respiratory Medicine, Hamamatsu Rosai Hospital
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CHIDA Kingo
the Second Department of Internal Medicine, Hamamatsu University School of Medicine
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Sugimura Haruhiko
The First Department of Investigative Pathology, Hamamatsu University School of Medicine
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Kono Masato
The Second Department of Internal Medicine, Hamamatsu University School of Medicine
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Kaida Yusuke
The Second Department of Internal Medicine, Hamamatsu University School of Medicine
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Nakamura Yutaro
The Second Department of Internal Medicine, Hamamatsu University School of Medicine
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