Thyroid Dysplasia in Wistar Hannover GALAS Rats

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概要

• 論文の詳細を見る

• Thyroid dysplasia was recognized in WistarHan GALAS rats and confirmed as a heritable congenital disorder. The gene or genes involved were not identified, but homozygous animals with thyroid dysplasia also exhibited stunted growth, had reduced pituitary gland growth hormone (GH) and were hypothyroid. Heterozygous animals exhibited thyroid dysplasia with normal thyroid hormonal homeostasis and no difference in the incidence of preneoplastic or neoplastic lesions in oncogenicity studies.

• 日本毒性病理学会の論文

著者

• Weber Klaus

  Harlan Laboratories Ltd.

• Ernst Rainer

  Schering AG Berlin

• Fankhauser Heinz

  RCC Ltd.

• Hardisty Jerry

  EPL Inc.

• Heider Wolfram

  Schering AG Berlin

• Stevens Karla

  Harlan Laboratories, Inc.

関連論文

• First Steps Towards an Understanding of a Mode of Carcinogenic Action for Vanadium Pentoxide
• Lesions in the Larynx of Wistar RccHanTM: WIST Rats
• Thyroid Dysplasia in Wistar Hannover GALAS Rats
• Lesions in the Larynx of Wistar RccHan^ : WIST Rats
• First Steps Towards on Understanding of a Mode of Carcinogenic Action for Vanadium Pentoxide
• Thyroid Dysplasia in Wistar Hannover GALAS Rats

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