Characterization of Maternal Antigen That Embryos Require (MATER/NLRP5) Gene and Protein in Pig Somatic Tissues and Germ Cells

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概要

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• Maternal effect genes produce mRNA or proteins that accumulate in the egg during oogenesis and control the developmental program until embryonic genome activation takes place. NLRP5 (NLR family, Pyrin domain containing 5), also called MATER (Maternal Antigen That Embryos Require) is one of the genes required for normal early embryonic development, although its precise function remains to be elucidated. The aim of the present study was to analyze the NLRP5 gene expression pattern and protein distribution in somatic tissues and germ cells in the pig. Reverse transcription was performed on mRNA from germinal vescicle (GV) oocytes and total RNA from spermatozoa and tissues from different organs. The transcript for NLRP5 gene was identified only in ovaries and oocytes. The presence of NLRP5 protein was detected only in ovaries by western blot analysis and immunohistochemistry.

著者

• Mariani Paola

  Livestock Genomics 2 Unit Parco Tecnologico Padano

• Pisani Laura

  Livestock Genomics 2 Unit Parco Tecnologico Padano

• Ramelli Paola

  Livestock Genomics 2 Unit Parco Tecnologico Padano

• Braglia Silvia

  Livestock Genomics 2 Unit Parco Tecnologico Padano

• Lazzari Barbara

  Statistical Genomics And Bioinformatics Unit Parco Tecnologico Padano

• Ceciliani Fabrizio

  Department Of Animal Pathology Hygiene And Veterinary Public Health Universita Degli Studi Di Milano

• MARIANI Paola

  Livestock Genomics 2 Unit, Parco Tecnologico Padano

関連論文

• Characterization of Maternal Antigen That Embryos Require (MATER/NLRP5) Gene and Protein in Pig Somatic Tissues and Germ Cells
• Characterization of Maternal Antigen That Embryos Require (MATER/NLRP5) Gene and Protein in Pig Somatic Tissues and Germ Cells

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