ディーゼル排気 (DE) 関連ナノ粒子の生体影響研究の課題

概要

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Nanoparticles have new chemical, electrical, optical and magnetic properties with different respondences to external stimuli (light, heat, voltage), compared to larger particles. Since nanoparticles will be applied in a variety of industrial fields such as chemistry, electronics, cosmetics, medicine, food, and environmental technology, the possibility of exposure to these nanoparticles in the workplace might increase. In the atmospheric environment, increase in nanoparticle concentration is reported in the roadside area during rush hour. There is a possibility of exposure to the ambient nanoparticles. Diesel engines release a large number of nanoparticles. However, little has been done on the exposure assessment and health and environmental risk assessment of both manufactured and ambient nanoparticles. In this paper, 1) results of the previous studies on the health effects of diesel particles are summarized, 2) behavior and translocation of nanoparticles in the human body are discussed using the previous toxicological and epidemiological studies on nanoparticles and the research issues on the health effect of nanoparticles in diesel exhaust are presented, 3) newly fabricated facilities for assessing health and environmental risk and our plan to investigate health risk assessment of nanoparticles using the facilities are introduced.
日本エアロゾル学会の論文