Chemical Examination of the Sponge Phycopsis sp.

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概要

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• Two new compounds 7α,8α-epoxy theonellin isothiocyanate (1) and 5α,8α-epidioxyergosta-6Z,22Z,25-trien-3β-ol (2) along with two known compounds, theonellin isothiocyanate (3) and theonellin formamide (4) have been isolated from the sponge Phycopsis sp. Compound 2 showed cytotoxic activity against HL-60 and U937 human cancer cell lines with IC50 values of 5.96±0.02 and 31.72±0.55 μg/ml, respectively.

• 社団法人 日本薬学会の論文

著者

• Kondempudi Chinni

  Natural Products Laboratory, Organic Chemistry Division-I, Indian Institute of Chemical Technology

• Singanaboina Rajaram

  Natural Products Laboratory, Organic Chemistry Division-I, Indian Institute of Chemical Technology

• Manchala Narasimhulu

  Natural Products Laboratory, Organic Chemistry Division-I, Indian Institute of Chemical Technology

• Gunda Venu

  Toxicology Unit, Biology Division, Indian Institute of Chemical Technology

• Janapala Venkateswara

  Toxicology Unit, Biology Division, Indian Institute of Chemical Technology

• Yenamandra Venkateswarlu

  Natural Products Laboratory, Organic Chemistry Division-I, Indian Institute of Chemical Technology

関連論文

• Chemical Examination of the Sponge Phycopsis sp.

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