Deoxymanoalides from the Nudibranch Chromodoris willani
スポンサーリンク
概要
- 論文の詳細を見る
Two sesterterpenes, deoxymanoalide (1) and deoxysecomanoalide (2), were isolated from the nudibranch Chromodoris willani collected in Okinawa and their structures determined on the basis of spectroscopic data and chemical conversions. The mollusk feeds on a sponge containing manoalide (3) and secomanoalide (4) and is likely to biotransform them into 1 and 2. Both 1 and 2 showed moderate antimicrobial activity against Escherichia coli and Bacillus subtilis and inhibited snake venom phospholipase A2 at 0.2 to 0.5 μM.
著者
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Tanaka Junichi
Department of Chemistry, Biology and Marine Science, University of the Ryukyus
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Higa Tatsuo
Department Of Chemistry Biology And Marine Science University Of The Ryukyus
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Uddin Mohammad
Department Of Human And Engineered Environmental Studies Graduate School Of Frontier Sciences Univer
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Otsuka Masahito
Department of Chemistry, Biology and Marine Science, University of the Ryukyus
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Muroi Toshinobu
Department of Chemistry, Biology and Marine Science, University of the Ryukyus
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Ono Atsushi
Diving Service Ono
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Hanif Novriyandi
Nagoya University
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Matsuda Seiko
Okinawa Prefectural Institute of Health and Environment
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Tanaka Junichi
Department Of Chemistry Biology And Marine Science And Graduate School Of Engineering And Science Un
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Uddin Mohammad
Department of Chemistry, Biology and Marine Science, University of the Ryukyus
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Higa Tatsuo
Department of Chemistry, Biology and Marine Science, University of the Ryukyus
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