Gallbladder Edema in Type 1 Diabetic Patient due to Delayed-type Insulin Allergy
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概要
- 論文の詳細を見る
A 29-year-old woman was diagnosed as having type 1 diabetes mellitus and received insulin aspart and NPH insulin (Novolin®N). On day 22, she had leg edema and right abdominal pain. The serum hepatobiliary enzyme levels were markedly elevated. Computed tomography revealed gallbladder edema. After an injection of human regular insulin and NPH insulin (Humacart®N), the elevated liver enzyme levels were no longer observed. Challenge testing demonstrated that protamine was the cause of her allergy. Furthermore, tests revealed increased VEGF levels. This is an extremely rare case with a delayed-type protamine allergy caused by Novolin®N resulting in gallbladder edema.
著者
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Shigetoh Makoto
川崎医科大学 内科学教室内分泌糖尿病
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Shigeto Makoto
Division Of Diabetes And Endocrinology Department Of Medicine Kawasaki Medical School
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KAKU Kohei
Division of Diabetes and Endocrinology, Department of Medicine, Kawasaki Medical School
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Kawasaki Fumiko
Division of Diabetes and Endocrinology, Department of Medicine, Kawasaki Medical School
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Kamei Shinji
Division of Diabetes and Endocrinology, Department of Medicine, Kawasaki Medical School
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Tatsumi Fuminori
Division of Diabetes and Endocrinology, Department of Medicine, Kawasaki Medical School
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Hamamoto Sumiko
Division of Diabetes and Endocrinology, Department of Medicine, Kawasaki Medical School
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Shimoda Masashi
Division of Diabetes and Endocrinology, Department of Medicine, Kawasaki Medical School
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Tawaramoto Kazuhito
Division of Diabetes and Endocrinology, Department of Medicine, Kawasaki Medical School
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Kanda Yukiko
Division of Diabetes and Endocrinology, Department of Medicine, Kawasaki Medical School
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Hashiramoto Mitsuru
Division of Diabetes and Endocrinology, Department of Medicine, Kawasaki Medical School
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Matsuki Michihiro
Division of Diabetes and Endocrinology, Department of Medicine, Kawasaki Medical School
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