Fatal TRALI Associated with Neutrophil Antibodies in a Recipient of Pre-Storage Leukocyte-Reduced Blood Components
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概要
- 論文の詳細を見る
A 53-year-old man developed possible transfusion-related acute lung injury (TRALI) after red cell component transfusion. The patient developed autoimmune neutropenia with the expression of neutrophil antibodies. Neutrophil aggregation, endothelial damage, and development of a large thrombus containing platelets were observed post mortem in his pulmonary vessels. The patient also had subacute organizing pneumonia. He received blood components treated with universal pre-storage leuko-reduction. Even though leukocytes in the blood components are reduced to a few million by this process, TRALI can be fatal, as was the case for this recipient, who had subacute organizing pneumonia in conjunction with immune-mediated neutropenia.
- 社団法人 日本内科学会の論文
著者
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Nomura Shosaku
Department Of Hematology Kansai Medical School
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Ishii Kazuyoshi
Department Of Applied Physics And Chemistry The University Of Electro-communications
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Kadota Eiji
Department Of Laboratory Medicine And Pathology Kishiwada City Hospital
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Ishii Kazuyoshi
Department of Hematology, Kishiwada City Hospital
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Shimizu Michiomi
Department of Hematology, Kishiwada City Hospital
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