Histopathologically-Diagnosed Splenic Metastasis in a Hepatocellular Carcinoma Case with Adrenal Metastasis

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概要

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• We encountered a patient with hepatocellular carcinoma (HCC), with adrenal gland metastasis, in whom splenic metastasis was diagnosed histopathologically. A 59-year-old man visited our hospital in May 2001 with chief complaints of abdominal distension and pretibial pitting edema. Multiple HCCs associated with HCV-positive liver cirrhosis were detected. Transarterial embolization (TAE) was performed a total of 4 times for HCCs. A left adrenal gland metastatic lesion was detected and it was found to increase in diameter from 3 cm to 6 cm over a four-month period; left adrenalectomy was performed in June 2002. Because of marked splenomegaly and findings of hypersplenism, the spleen was also resected. Although no metastatic lesions were evident on macroscopic examination of the spleen, a small metastatic lesion from moderately differentiated HCC, approximately 0.5 mm in diameter, was detected histopathologically. Splenic metastasis from HCC is rare, usually occurring with metastases involving other organs. Our patient also had adrenal gland metastasis. Therefore, hematogenous metastasis to the congested spleen via the systemic circulation was suspected.

• 社団法人　日本内科学会の論文
• 2004-06-01

著者

• Hayashi N

  Osaka Univ. Graduate School Of Medicine Suita Jpn

• Saito Akiko

  Institute Of Gastroenterology Tokyo Women's Medical University

• Saito Akiko

  Gastroenterological Medicine Tokyo Women's Medical University

• Hayashi Naoaki

  The Departments Of Gastroenterology Tokyo Women's Medical University

• Hanada Kenji

  The Departments Of Gastroenterology Tokyo Women's Medical University

• Takasaki Ken

  Department Of Surgery Institute Of Gastroenterology Tokyo Women's Medical University

• Takasaki Ken

  Department Of Medicine Institute Of Gastroenterology Tokyo Women's Medical University

• Nozawa Hideki

  The Departments Of Gastroenterology Tokyo Women's Medical University

• Katagiri Satoshi

  Department Of Surgery Institute Of Gastroenterology Tokyo Women's Medical University

• Ohtsubo Takehito

  Gastroenterological Surgery Tokyo Women's Medical University

• Katsuragawa Hideo

  Department Of Surgery Institute Of Gastroenterology Tokyo Women's Medical University

• SAITO Akiko

  the Departments of Gastroenterology, Tokyo Women's Medical University

• HARUYAMA Koichi

  the Departments of Gastroenterology, Tokyo Women's Medical University

• YAMADA Michiyo

  Gastroenterological Surgery, Tokyo Women's Medical University

• KATAGIRI Satoshi

  Gastroenterological Surgery, Tokyo Women's Medical University

• KATSURAGAWA Hideo

  Gastroenterological Surgery, Tokyo Women's Medical University

• OTSUBO Takehito

  Gastroenterological Surgery, Tokyo Women's Medical University

• TAKASAKI Ken

  Gastroenterological Surgery, Tokyo Women's Medical University

• Yamada Michiyo

  Gastroenterological Surgery Tokyo Women's Medical University

• Haruyama Koichi

  The Departments Of Gastroenterology Tokyo Women's Medical University

• Katsuragawa Hideo

  Department Of Medicine Institute Of Gastroenterology Tokyo Women's Medical University

• Otsubo Takehito

  Department Of Surgery Institute Of Gastroenterology Tokyo Women's Medical University

• Saito Akiko

  Department Of Medicine Institute Of Gastroenterology Tokyo Women's Medical University

• Otsubo Takehito

  Gastroenterological Surgery Tokyo Women's Medical University

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