Long-Term Intensive Insulin Therapy for Japanese Patients with Type 2 Diabetes Mellitus

概要

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Objective To determine the clinical usefulness of long-term intensive insulin therapy in Japanese patients with type 2 diabetes. Patients and Methods Various clinical indicators and potential of withdrawal from insulin therapy were investigated in 20 type 2 diabetic patients receiving treatment in the outpatient clinic over a period of 8 years after starting intensive insulin therapy between April 1997 and March 1999. Results The mean glycated hemoglobin (HbA1c) was approximately 6.5%, and there was no significant increase in insulin dose over a period of 8 years after commencement of intensive insulin therapy. Withdrawal from insulin therapy could be sustained in previously untreated patients. Conclusion Our results indicated the clinical usefulness of intensive insulin therapy over the long term in Japanese patients with type 2 diabetes and that such therapy could be especially useful for previously untreated patients.
社団法人日本内科学会の論文