Auto-Regulated Blood Flow in the Cerebral-Vasculature
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概要
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The Circle of Willis (CoW) is a ring-like arterial structure located in the base of the brain, responsible for the distribution of oxygenated blood throughout the cerebral mass. Among the general population, approximately 50% have a complete CoW, and among a multitude of possible anatomical variations, vessels absent from the CoW are common. Certain conditions such as a build up of atherosclerotic plaque on the arterial wall can result in ischaemic damage and stroke-like symptoms. A 3D computer model has been developed based on the results of MRA scans of 3 patients cerebral-vasculature incorporating a numerical algorithm to simulate the bodys autoregulation mechanism. The intention of the present study was to investigate different anatomical states, including different vessels missing from the circle whilst occluding the main afferent arteries such as the Internal Carotid and Basilar Arteries.
著者
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David Tim
Centre For Bioengineering University Of Canterbury
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MOORE Steve
Centre for Bioengineering University
関連論文
- PATIENT SPECIFIC RESPONSE TO STENOSIS IN THE CIRCLE OF WILLIS(1D1 Cardiovascular Mechanics I)
- CFD STUDY ON MASS TRANSPORT TO SACCULAR ANEURYSMS AT ARTERIAL BEND(1D1 Cardiovascular Mechanics I)
- DYNAMIC MYOGENIC AUTOREGULATION IN THE RAT KIDNEY : A WHOLE-ORGAN MATHEMATICAL MODEL(1D1 Cardiovascular Mechanics I)
- Auto-Regulated Blood Flow in the Cerebral-Vasculature