Minocycline-Induced Acute Eosinophilic Pneumonia: Controversial Results of Lymphocyte Stimulation Test and Re-challenge Test
スポンサーリンク
概要
- 論文の詳細を見る
We report an instructive case of minocycline-induced eosinophilic pneumonia confirmed by re-challenge test, in which a preceding lymphocyte-stimulation test indicated acetaminophen as the etiologic agent. A 55-year-old woman developed high fever and lung infiltrates with pulmonary eosinophilia after exposure to minocycline, acetaminophen, theophylline and procaterol. All of the medicines were discontinued, resulting in prompt improvement. The lymphocyte stimulation tests provided a positive result for acetaminophen, but not for the other medicines; however, a negative result was given by a re-challenge test with acetaminophen. In contrast, symptoms and hypoxemia reappeared when minocycline was re-administered. We would like to emphasize that lymphocyte stimulation test results need to be carefully interpreted for individual drugs.
- 社団法人 日本内科学会の論文
著者
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Matsuno Osamu
Division Of Respiratory Medicine Department Of Brain And Nerve Oita University Faculty Of Medicine
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Miyazaki Eishi
Division of Pulmonary Disease, Oita University Faculty of Medicine
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Okubo Toshiyuki
Division of Pulmonary Disease, Oita University Faculty of Medicine
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Ono Emiko
Division of Pulmonary Disease, Oita University Faculty of Medicine
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Ando Masaru
Division of Pulmonary Disease, Oita University Faculty of Medicine
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Nureki Shin-ichi
Division of Pulmonary Disease, Oita University Faculty of Medicine
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Kumamoto Toshihide
Division of Neurology and Neuromuscular Disorders, Department of Brain and Nerve Science, Oita University Faculty of Medicine
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