Co-existence of Mycobacterium tuberculosis and Mycobacterium intracellulare in One Sputum Sample
スポンサーリンク
概要
- 論文の詳細を見る
An 81-year-old man was admitted to the hospital with a severe sore throat and a low grade fever. A chest radiograph showed bilateral diffuse reticulonodular shadows. By fluorescent stain for mycobacteria, his sputum smear showed acid-fast bacteria. The initial polymerase chain reaction (PCR) of his sputum revealed Mycobacterium intracellulare (M. intracellulare), but not Mycobacterium tuberculosis (M. tuberculosis). However, a repeat PCR was performed because M. tuberculosis could not be ruled out due to his clinical symptoms and chest imaging. The second PCR detected both M. intracellulare and M. tuberculosis. From the standpoint of infection control, this case illustrates the possibility that M. tuberculosis could be a threat if a second PCR is not done. While PCR is a useful exam for diagnosing M. tuberculosis, it can produce false negative results. Therefore, for diagnosing tuberculosis, particularly in a case such as the present case, a second PCR, which is not normally necessary, should be done.
著者
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UEKI SHIGEHARU
Department of Clinical and Laboratory Medicine, Akita University School of Medicine
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Yamaguchi Kazutoshi
Department Of Clinical And Laboratory Medicine Akita University School Of Medicine
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Ueki Shigeharu
Department Of Clinical And Laboratory Medicine Akita University School Of Medicine
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Kayaba Hiroyuki
Department Of Clinical And Laboratory Medicine Akita University School Of Medicine
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Chiba Takahito
Department Of Clinical And Laboratory Medicine Akita University School Of Medicine
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Chihara Junichi
Department Of Clinical And Laboratory Medicine Akita University Graduate School Of Medicine
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Takeda Masahide
Department Of Material Chemistry Graduate School Of Engineering Kyoto University
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Ito Wataru
Department Of Biological Science And Technology Faculty Of Engineering The University Of Tokushima
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Ito Wataru
Department of Clinical and Laboratory Medicine, Akita University School of Medicine
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Kobayashi Noriko
Infection Control Team, Akita University Hospital
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Konno Keiko
Central Clinical Laboratory, Akita University Hospital
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Takahashi Tomoe
Infection Control Team, Akita University Hospital
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Tatsuko Rumi
Central Clinical Laboratory, Akita University Hospital
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Tomita Noriko
Infection Control Team, Akita University Hospital
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Tanigai Tomomi
Department of Clinical and Laboratory Medicine, Akita University School of Medicine
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Sato Kazuhiro
Infection Control Team, Akita University Hospital
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